Ladner JE, Parsons JF, Rife CL, Gilliland GL, Armstrong RN
Texture: Cream Consistency: Velvety-rich Scent: Natural, aromatic rose *This product is free from soy, nuts, gluten, fish, milk, corn, phthalates, sulfates, parabens, talc, and mineral oil
It is also hydrophilic, suggesting problems in transporting it across the BBB (unlike PBN) (Halliwell and Gutteridge, 2015)
A shift toward pro-inflammatory immune phenotypessuch as increased M1-type macrophage infiltration and elevated levels of cytokines like Tumor necrosis factor-alpha (TNF-) and Interleukin-6 (IL-6)has been shown to inhibit osteogenesis, stimulate osteoclastogenesis, and ultimately accelerate bone loss (Sun et al., 2021)