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26 Engaging adolescents, employing brief interventions that promote self-management and referring to youth drug and alcohol, community mental health and paediatric services are often needed early in the drug use spectrum to prevent substance misuse and to achieve positive behaviour change (Box 5)

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A 2021 publication by the Campaign for Tobacco-Free Kids , a non-profit organization, stated that about 80% of the world's smokers lived in low and middle income countries, and that if current trends were to continue, about a billion people could die from smoking related diseases in the 21st century

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