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PNPO-PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity

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doi: 10.3389/fphar.2025.1528208 Received 14 November 2024 Accepted 02 April 2025 Published 10 April 2025 Volume 16 - 2025 Edited by Yanggan Wang, Wuhan University, China Reviewed by Yi Zhu, Chengdu University of Traditional Chinese Medicine, China Baonian Liu, Shanghai University of Traditional Chinese Medicine, China Updates Copyright 2025 Chen, Fu, Zhou and Wu