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Moreover, in facing various pathological challenges, the mammalian heart, which possesses high levels of mitochondria and weak antioxidant capacity, is susceptible to oxidant production and oxidative damage

In vitro studies have revealed that claudin expression is significantly downregulated in anaplastic astrocytoma and GBM cell cultures

On the dose-response curve of the effect of intraperitoneal BPC-157 on the flinching response in the formalin test, BPC-157 led to significant suppression of the flinches in a dose-dependent manner in phase 1 but showed little effect in phase 2 (Fig