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But the primary concern is the risk of ochronosis, a rare but challenging condition where long-term overuse paradoxically causes darkening of the skin, says Francesa Lewis, MD, a board-certified dermatologist in Delray Beach, Florida

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy (vol 47, pg 73, 2015)

Gln is a conditionally essential amino acid whose biosynthesis is often insufficient to adequately respond to cell demands, particularly under certain physio-pathological conditions

With additional hyaluronic acid and vitamin C, this supplement helps fight signs of aging and maintain skins moisture balance