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Extensive evidence shows that the intestinal microbiota in UC differs markedly from that of healthy individuals, with depletion of beneficial commensals and expansion of potentially harmful taxa (Table 1)

EC 50 -values were determined from the concentration-response curves using a three-parameter logistic equation

3.4 Anticancer mechanisms of phytosterols and alkaloids 3.4.1 Interference with cholesterol metabolism and tumor cell membrane structure Phytosterols such as -sitosterol are structurally similar to cholesterol and competitively interfere with cholesterol utilization by tumor cells (78)