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demonstrated that T cells increase flux through the PPP upon activation and that activated murine CD8+ and CD4 + T cells rely predominantly on G6PD for the production of NADPH

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Furthermore, CS/MTO-Cu@AMI enhances anti-tumor immunity by stimulating the cGAS-STING pathway, which plays a critical role in promoting immune surveillance and response against tumors, making it a promising candidate for combination therapies targeting immune checkpoints (Tian et al., 2023)

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