[DOI] [PMC free article] [PubMed] [Google Scholar] 311.Ehudin M.A., Golla U., Trivedi D., Potlakayala S.D., Rudrabhatla S.V., Desai D., Dovat S., Claxton D., Sharma A
For patients with confirmed pernicious anaemia or malabsorption disorders, injectable therapy remains the recommended first-line treatment according to NICE CKS guidance, as oral supplementationregardless of dosecannot reliably correct deficiency in these circumstances
however, its conventional transcutaneous delivery is significantly limited by inadequate tissue penetration and energy attenuation, leading to inconsistent clinical outcomes
In addition, it also highlights how the tissue microenvironment may strongly influence progesterone function