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Reactive aldehydes including malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), formed during lipid peroxidation, exert cytotoxic effects that ultimately lead to cell death

It was suggested that the levels of HIF-1 methylation were enhanced in alcoholic AP compared to non-alcoholic AP

doi: 10.1001/jama.2022.20045 Ruiz-Colon K et al (2014): Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature