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in the literature studied in synergy with GHRPs as a complementary mechanism of GH secretion (the GHS cluster)

The combination of the lysosome disruptor siramesine and the tyrosine kinase inhibitor lapatinib increased the expression of TF and reduced the expression of FPN1 in breast cancer cells, thereby promoting iron overload in the lysosome and ultimately inducing ferroptosis (Ma et al., 2016)