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These contradictory clinical findings could depend on the selection, application, and interpretation methodology of functional outcome measures for testing individuals with cognitive impairment

Key takeaways Metformin is a medication approved for treating type 2 diabetes, but healthcare providers sometimes prescribe it off-label for other conditions and weight management

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2d) revealed constitutive induction of CYP2E1 (1.8-fold) and ALDH1A1 (1.4-fold) at both protein and enzymatic activity levels in KO livers relative to WT livers (Fig