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Despite this, it is well known that neuroprotective effect of coffee is not due to caffeine alone, but to other bioactive components, such as polyphenols, including phenolic acid, i.e., caffeic acid, ferulic acid, p-coumaric acid, chlorogenic acid, and quinin acid

As numerous studies have identified a close relationship between gut microbiota and functional constipation 60,67 , promoting duodenal mucus secretion may therefore indirectly affect morphine-induced constipation

None of the participants received any compensation for their participation

Recently, a widespread belief has emerged that Vitamin B12 causes weight gain