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Lycium ruthenicum ethanol extract (LRE) mitigated colonic damage, restored immune homeostasis, and inhibited NLRP3 inflammasome assembly by suppressing MAPK activity in DSS (dextran sulfate sodium)-induced colitis mice (Zong et al., 2020)

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445 Additionally, intracellular HSP90, which is involved in the activation of both innate and adaptive immune responses, has been implicated in autoimmune processes