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Annu Rev Biophys Bioeng

Notably, early studies demonstrated that 1,25(OH)D could inhibit the DNA-binding activity of NF-B in human MRC-5 fibroblasts without preventing the nuclear translocation of its p50 or p65 subunits

Key mechanisms of erianin in overcoming cancer drug resistance include the regulation of drug transport systems and targeting of key components of the cytoskeleton, as well as the regulation of signaling pathways and direct cytotoxicity (108,109)