2-AB metabolism in vitro and in vivo For in vitro synthesis of 2-AB, 2-oxobutyric acid was mixed with 50 mM Tris-HCl, 0.1 mM pyridoxal-5-phosphate, 0.1 mM glutamic acid, and 5 units of aspartate aminotransferase (WAKO)

30% curcuminoids) 300 mg CurcuPrime Tetrahydrocurcumin 200 mg Luteolin 200 mg Resveratrol (Polygonum cuspidatum Sieb.) (Root) 50 mg Pterostilbene (Pterocarpus marsupium) (Wood) 50 mg 2x DNA Prime ac-11 Cat's Claw Aqueous Extract (Uncaria tomentosa) (bark) (standardized to 8% carboy alkyl esters, CAEs) 700 mg Activated BroccoRaphanin (Broccoli concentrate from seed and myrosinase enzyme) 300 mg Sulforaphane Glucosinolate (as Glucoraphanin) 30 mg Buckwheat Peptides 20:1 200 mg 2-HOBA (Hobamine) 100 mg L-Ergothioneine (as MitoPrime) 10 mg 3x Enhance Arginine Alpha-Ketoglutarate 500 mg Trimethylglycine (TMG) (as Betaine Anhydrous) 500 mg Bergamont Orange Extract (citrus bergamia)(Fruit) (Bergamonte) (38% Bergamot Polyphenolic Fraction comprised of Neohesperidin, Naringin, Neoeriocitrin, Brutierifin and Melitidin) 250 mg Epigallocatechin Gallate (EGCG) (from Green Tea 98% Extract) 100 mg Taxifolin (from Dihydroquercetin) 10 mg Spermidine 10 mg Other Ingredients: Vegetable Capsule (Hypromellose, Titanium Dioxide), Vegetable Capsule (Hypromellose, Titanium Dioxide), Microcrystalline Cellulose, Magnesium Stearate (Vegetable), Silica, Vegetable Capsule (Hypromellose), Vegetable Capsule (Hypromellose, Titanium Dioxide) Dosage: Take 1 full sachet pack daily, in the morning on an empty stomach at least 1 hr before eating a meal, or as recommended by your healthcare professional If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use

These compounds are recognized as biomarkers of oxidative stress in cardiovascular and neurological disorders (Gil et al., 2018
The Expression Of Programmed Death 1 Ligand (PD-L1) In The Tumor and Tumor Infiltrating Macrophages Predicts Overall and Disease Free Survival in Surgically Resected Pathologic Stage I Non-Small Cell Lung Cancer