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In particular, they pointed out that although NRF2 has been traditionally considered as a tumor suppressor because of its cytoprotective functions [320], a growing number of studies have shown a strong NRF2 activation at certain stages of cancer [318, 321]

CAR 16, 261277

While research indicates that it does not significantly impact growth hormone levels, IGF-1, or glucose metabolism, long-term studies on its safety are still limited