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Tap an ingredient for the detail: Vitamin ECytochrome P450 3a4 (cyp3a4) Substrates Moderate Interaction Summary Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates

The mechanism is plausible

The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development

J Neurochem (1999) 73(3):130917.10.1046/j.1471-4159.1999.0731309.x 12 PerierCTieuKGuganCCaspersenCJackson-LewisVCarelliVet alComplex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage