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This was in disagreement with the findings reported by Busquets et al

In mouse models of chemotherapy-induced POF, the transplantation of human amniotic epithelial cell-derived exosomes administered both directly into damaged ovaries and systemically substantially enhances ovarian function by augmenting the quantity of healthy primordial, primary, secondary, and mature follicles, which are otherwise diminished by chemotherapeutic agents

(Peptide Sciences) FOXO4 expression is increased in senescent cells, and interfering with FOXO4 via shRNA or peptide competition leads to apoptosis of those cells

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