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Depending on the product, lubricant may increase vaginal epithelial inflammation and dysbiosis (137, 138), affect vaginal microbiota through antimicrobial preservatives such as parabens or glycerine (139), and/or alter microbiota through pH and osmolality (139)

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Cigar Warning Plans for Packaging You must submit a proposed warning plan to FDA no later than August 10, 2017, or 12 months before advertising or commercially marketing a cigar product, whichever is later (21 CFR 1143.5(c)(3))

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