Vinciguerra, The costs and benefits of senotherapeutics for human health
Key areas of investigation include: Gastrointestinal : Demonstrated protection against NSAID-induced ulcers, inflammatory bowel disease models, and esophageal damage in multiple animal studies Musculoskeletal : Accelerated healing of transected Achilles tendons, quadriceps muscles, and medial collateral ligaments in rat models Neurological : Neuroprotective effects in models of traumatic brain injury, nerve crush injury, and dopaminergic system damage Organ protection : Hepatoprotective, cardioprotective, and nephroprotective effects demonstrated in various toxicity models The primary limitation is that all evidence comes from animal models
Until clinical trials provide the necessary safety and efficacy data, conservative approaches grounded in existing evidence serve patients, clients, and the wellness community most effectively
It also helps in the formation of collagen, providing anti-aging properties in the skin