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Lab Markers: Progress is monitored with lab work at baseline, 3 months, 6 months, and 12 months

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Wnt/-catenin signaling plays a protective role in the Mdr2 knockout murine model of cholestaticliver disease

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10.1038/s12276-019-0216-4 62 HasanuzzamanM.AlamM.RahmanA.HasanuzzamanM.NaharK.FujitaM.et al (2014)

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Under physiological conditions, KEAP1 mediates NRF2s constitutive proteasomal degradation (McMahon et al., 2003) while BACH1 acts as transcriptional antagonist of NRF2s target genes (Zhang and Hannink, 2003)

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