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Functioning as a neuromodulator, DSIP influences the activity of GABAergic, glutamatergic, and opioid systems, which are integral to sleep, mood regulation, and pain perception ( 2, 6, 7 )

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Prevalence of Alzheimer's disease dementia in the 50 US states and 3142 counties: A population estimate using the 2020 bridgedrace postcensal from the National Center for Health Statistics