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Aging cell 2010;9, 667-684

Wu C-L, Kimmerling KA, Little D, Guilak F

From an anti-inflammatory perspective, BPC-157 has been shown to attenuate the expression of pro-inflammatory cytokines like TNF- and IL-6 in certain inflammatory models

One possible explanation is that the beneficial effects of lowering Hcy are offset by the direct adverse effects of B vitamins supplementation (particularly with high-dose folate), or are associated with the pro-inflammatory and pro-proliferative effects of B vitamins on advanced AS lesions (128)