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Across human studies and reviews, adverse effects are uncommon at typical supplemental intakes, and when side effects do occur, they are usually mild and gastrointestinal in nature.12 13 44 A safety-focused review published in European Review for Medical and Pharmacological Sciences summarized available clinical and non-clinical data on myo-inositol and reported that only very high intake (around 12g per day) was consistently associated with side effects specifically mild gastrointestinal symptoms such as nausea, gas/flatulence, and diarrhea.44 The authors also noted that the severity of these effects did not increase with higher doses

Research shows potential applications in age related muscle changes through its effects on mitochondrial quality control and inflammatory processes

SNAC (Salcaprozate Sodium) changes the game

It also increases collagen III for tissue flexibility and drives collagen IV production up by a remarkable 25.4-fold when combined with hyaluronic acid