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DHT is responsible for increased sebum production by the sebaceous glands and exacerbates acne lesions (185, 186)

It activates both the GLP-1 pathway (which reduces appetite, slows gastric emptying, and increases feelings of fullness) and the GIP pathway (which enhances insulin response and supports fat metabolism)

It can support joint function and expedite muscle healinguseful in sports medicine and rehabilitationand may help address age-related declines in regenerative capacity to preserve vitality

PDK4 has been reported to block a metabolic switch from glycolysis to predominantly fatty acid synthesis and contribute to ferroptosis resistance in certain cancer cells, such as pancreatic ductal adenocarcinoma (PDAC) cells [18,19]