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In clinical trials, a single oral dose of macimorelin (0.5 mg/kg) was shown to be reliable and accurate for diagnosing adult GHD (49)

Proc Am Assoc Cancer Res 38:342, 1997

886 The intestinal microbiota metabolite capsiate is negatively correlated with cartilage degeneration score in OA mice, and capsiate reduces ferroptosis dependent osteoarthritis both in vivo and in vitro, through activation of SLC2A1 and inhibition of HIF-1