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Description

A significant fall in Tregs following birth and a recovery of the immune response to its pre-pregnancy level may cause autoimmune thyroid disease to develop or worsen

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4b(b)), suggesting that HLAH-z13 promotes endosome-escaping activity releasing biotin-z13 from endosomes to the cytoplasm

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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 7% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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