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MOTS-c is not currently prescribable through legitimate compounding pharmacies

Some use injections for faster repletion and later switch to an oral routine

Exon Publications, Australia, pp 6582 Esse R, Barroso M, Tavares de Almeida I, Castro R (2019) The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art

Key considerations from available evidence: No direct hormonal mechanism linking tirzepatide to menstrual disruption has been identified Metabolic improvements (reduced insulin resistance, decreased androgens) may benefit women with PCOS The magnitude and rapidity of weight loss correlate with likelihood of temporary menstrual changes Long-term data on reproductive outcomes remain limited Healthcare providers should counsel women of reproductive age about potential menstrual changes when initiating tirzepatide