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References InsightGlobal, "Why Decentralized Clinical Trials Bring in a New Era of R&D," Feb 11, 2026
The ferroptosis-related genes, including Glutathione Peroxidase 4 ( Gpx4 ), Solute Carrier Family 7 Member 11 ( Slc7a11 ), Acyl-CoA Synthetase Long Chain Family Member 4 ( Acsl4 ), Lysophosphatidylcholine Acyltransferase 3 ( Lpcat3 ) , Apoptosis Inducing Factor Mitochondria Associated 2 ( Aifm2 ), and GTP Cyclohydrolase 1 ( Gch1 ), and the pyroptosis-related genes, including Caspase 1 ( Casp1 ), Caspase 11 ( Casp11 ) , Gasdermin D ( Gsdmd ), and Gasdermin E ( Gsdme ), were analyzed by qPCR
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In contrast, Staphylococcus aureus contains five major low-molecular-weight thiols besides glutathione 38 , including bacillithiol, coenzyme A and cysteine 39 , and ergothioneine (data not shown), which together contribute to its cellular redox balance and defense against oxidative and other stressors, while maintaining CoASH acyl-transfer chemistry
