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Despite the reduction in the incidence and mortality of malaria over the past decade, there is a global emergence and gradual spread of antimalarial drug resistance, which has prompted significant efforts to determine the molecular mechanisms governing the biology of the parasite, either to counter this resistance or to propose alternative therapeutic targets

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In MCI individuals, the prevalence of depression is about 32% ( Anxiety is reported as the third most common NPS in AD (Teri et al., 1999

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