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Dombrowski Y, Peric M, Koglin S, Ruzicka T, Schauber J: Control of cutaneous antimicrobial peptides by vitamin D3

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Potential risks and contraindications Given the limited understanding of DSIPs mechanisms and effects in humans, certain risks and contraindications must be taken into consideration: Unknown long-term effects : The long-term safety of DSIP has not been well-established, and the potential risks associated with chronic use remain unclear