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Physiologically based pharmacokinetic modeling to characterize acetaminophen pharmacokinetics and N-acetyl-p-benzoquinone imine (NAPQI) formation in non-pregnant and pregnant women

The mitochondrial antioxidant systems such as TrxR and Trx, GPx, and SOD2 play a coordinate role in preserving cellular redox tone

Key Characteristics MOLECULAR PROFILE Formula: C 14 H 22 CuN 6 O 4 Weight: 401.9 g/mol CAS: 89030-95-5 Structure: Gly-His-Lys (with bound copper) PHYSICAL PROPERTIES Form: Blue crystalline powder (the blue color comes from the copper) Solubility: Highly water-soluble Natural Occurrence: Found in human plasma, saliva, and urine Storage: Keep refrigerated 3646 F (28 C), protect from light Related products CJC-1295 $60.00 $95.00Price range: $60.00 through $95.00 TB-500 $60.00 $90.00Price range: $60.00 through $90.00

ACS Chem Neurosci 12(13):25422552 Ali AE, Mahdy HM, Elsherbiny DM et al (2018) Rifampicin ameliorates lithium-pilocarpine-induced seizures, consequent hippocampal damage and memory deficit in rats: impact on oxidative, inflammatory and apoptotic machineries [J]