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Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11

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Vega-Naredo, I., Cunha-Oliveira, T., Serafim, T

Hepatic ischemia-reperfusion impairs blood-brain barrier partly due to release of arginase from injured liver