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Glutamine is then released to the synapse and taken up by adjacent neurons, where it is converted to glutamate and -aminobutyric acid (GABA), which are then repackaged into vesicles and again released in the synapse as neurotransmitters [167,168]

Hybrid receptor activation may produce metabolic effects (glucose uptake, anti-lipolysis) that are not strictly part of IGF1R-mediated anabolism

Beyond folate and methylation support therapy, addressing gut health, dysbiosis, and leaky gut is critical in reducing autoimmune activity and optimizing folate metabolism

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