The hypothesis behind the LMR is that the smaller mannitol (6.7 ) can pass via the pore pathway and can be considered as a marker for the total small intestinal surface, while the larger disaccharide lactulose (9.5 ) will only pass the larger pores of the leak pathway in the crypt region and at sites where the barrier is damaged (13)
Samples were mounted onto glass slides using water as a medium and investigated under a Leica (DMI 6000 CS AFC Bino inverted microscope) TCS SP8 instrument
Jaka Vukojevi, Borna Vrdoljak, Dominik Malekinui, Marko Siroglavi, Marija Milavi, Kolenc, D., Alenka Boban Blagai, Lovorka Batelja, Domagoj Drmi, Sven Seiverth, & Predrag Sikiri
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