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Increase tirzepatide to therapeutic dose (12.515mg weekly), ensure 5-amino-1MQ is dosed consistently at 100mg daily, and implement structured dietary intake with adequate protein (1.62.2g/kg) to support the catabolic shift both compounds induce

Patients in our Doral clinic who complete both phases consistently report more visible skin texture changes than those who stop early

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Overview 5-Amino-1MQ is classified as a potent and selective NNMT inhibitor that appears to preserve both S-adenosylmethionine (SAM) and nicotinamide, potentially enhancing NAD+ availability and cellular energetics