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3.2.2 The Met/cystine cycle and other amino acid pathways Beyond the direct uptake of extracellular cystine, cells can also generate cysteine via the methionine (Met) cycle and transsulfuration pathway (86)

Mitochondrial thiols were detected by measuring the MFI of MBB in CD19 Tom20 + (Abcam ab186734) isolated mitochondria from the enriched FoB and MZB fractions

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Further, proliferation and progression of tumor are controlled by the subsequently reprogrammed TME such as redox potential alteration [27], nutrient and oxygen uptake (hypoxia conditions) changes [28], and blood flow alteration [29] in the due time course