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Researchers became interested when early studies revealed that these peptides dont just work in parallelthey actually enhance each others mechanisms

[DOI] [PubMed] [Google Scholar] Gonzlez-Gordo S, Rodrguez-Ruiz M, Lpez-Jaramillo J, Muoz-Vargas MA, Palma JM, Corpas FJ

Avoid mixing with vitamin C or niacinamide-heavy products in the same step to prevent potential interactions.

Neuropharmacology 58(3):624631 Gourgiotis I, Kampouri NG, Koulouri V, Lempesis IG, Prasinou MD, Georgiadou G, Pitsikas N (2012) Nitric oxide modulates apomorphine-induced recognition memory deficits in rats