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The results of the statistical analysis were verified for changes in individual indicator values (growth inhibition, induction of promoter recA and ROS synthesis) for the compounds under consideration and their mixtures at concentrations of 0.01, 0.10, 1, 10, 100 mg/L and incubation times resulting from the conditions described in the analytical methodology
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Furthermore, by blocking the PI3K/Akt/mTOR signaling pathway, deltonin could also reduce the expression levels of important DNA-repair enzymes, such as Rad51 and murine double minute (MDM)2 (155)
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