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10.1038/s41531-021-00182-x NPJ Parkinsons Dis

Key findings include: Dose-dependent improvements in neurological function scores at doses 2.5 ml/kg in rat models Reduced infarct volumes in middle cerebral artery occlusion (MCAO) models Enhanced functional recovery when combined with rehabilitation protocols Protection against excitotoxicity and oxidative stress in acute phase Studies using embolic stroke models showed that Cerebrolysin at 5 ml/kg significantly reduced lesion volume and improved sensorimotor outcomes when treatment began 4 hours post-stroke[8]

Methylcobalamin is the bioactive form of B12 and does not require conversion

The choice between these peptides may depend on the specific joint condition: AOD-9604 may be more appropriate for cartilage-focused osteoarthritis applications, while BPC-157 might be preferred for soft tissue injuries