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The DSM-5 defines tobacco use disorder as a problematic pattern of tobacco use leading to clinically significant impairment or distress, as manifested by at least two of the following, occurring within a 12-month period. When an individual uses tobacco for more than a year and a minimum of two of the following sub-features appear, the disorder is diagnosed

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95% CI: 1.231.46) cancer, respectively

For most of the tobacco varietals that we produce such as Besuki NOTA, Voor Oogst Jatim, Kasturi and Madura, and Lombok FCV we begin with four months of rice paddies, then proceed to the main tobacco crop for another four months, and close the growing year with four months of corn. However, the cycle looks different for Besuki NO, which begins with two four-month-long periods of paddy and concludes with four months of tobacco