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Description

Destruction of oxidatively-damaged RBCs is accomplished extravascularly by macrophages in the reticuloendothelial system 56

Redox homeostasis disruption is responsible for synaptic dysfunction, neuroinflammation, and disrupted neuronal signaling, worsening the fundamental symptoms of ASD

& Gevrek, M

Capillary DPS cutoffs based on CSF biomarker positivity Exploratory diagnostic accuracy metrics were derived in a subset of individuals ( n = 176) with paired capillary and CSF A42/p-tau181 metrics, at a prevalence of 56.3% of CSF biomarker positivity