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Terzi A, Roeder H, Weaver CJ, Suter DM (2020) Neuronal NADPH oxidase 2 regulates growth cone guidance downstream of slit2/robo2

10.1073/pnas.1309426111 Proc

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(2025) discovered that Talaromyces purpurogenus , enriched in the gut of PCOS patients, produces the metabolite AT-C1, which suppresses the AhR signaling pathway and reduces IL-22 secretion, thereby inducing PCOS-like symptoms ( 6 Therapeutic modulation of the microbiome in PCOS In recent years, despite growing research interest in the gut microbiome, clinical trials targeting microbiome-based therapies for PCOS remain limited