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We found that Gclc ablation prevented the formation of T1 B cells by 2 weeks of age, indicating that a block in the B cell differentiation process occurred at the very early stage in the spleen (Fig

[Google Scholar] 20.Yan L., Guo M.-S., Zhang Y., Yu L., Wu J.-M., Tang Y., Ai W., Zhu F.-D., Law B.Y.-K., Chen Q., et al

10.1002/ptr.4970 65 RoganovicM.PantovicS.DizdarevicS

In BMAL1-knockout mice, pericytes progressively detach, extracellular matrix deposition is reduced, and tight junctions disassemble, leading to unstable neovasculature and loss of BBB integrity (79)