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& Widdop, R

Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism ( MITOCHONDRIAL ROS GENERATION AND DEFENSE Reactive oxygen species can be generated in several intracellular sites, including cytosol, peroxisomes, plasma membrane, and ER

30 FulnecekJ.MatyasekR.VotrubaI.HolyA.KrizovaK.KovarikA

Abstract Airway cellular dysfunction is a differentiating feature of severe asthma in children that may be related to an imbalance of the antioxidant, glutathione (GSH)