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In 2018, the leading causes of death due to cardiovascular disease in the U.S were (CDC): Coronary heart disease (42.1% of deaths) Stroke (17.0% of deaths) High blood pressure (11.0% of deaths) Heart failure (9.6% of deaths) Diseases of the arteries (2.9% of deaths), and Other (17.4% of deaths) The term cardiovascular disease may be used to refer to heart conditions that affect the blood vessels, including stroke and peripheral arterial disease

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Most doctors knew nothing about nitrous fumes and would pronounce a case heart failure or heat prostration