A combination of behavioural and pharmacological support is up to 4 times more effective than no help or over the counter nicotine replacement therapy (NRT)
On the other hand, natural nicotine products are regulated, promoted, and marketed as tobacco products and drugs
It originated in in the East, in the Middle East, it coming out of the desert tradition, right, the Desert Fathers and these were folks who didn't live in communities in many cases, but actually tried to escape their their communities and to dwell as hermits and contemplatives and go through all kinds of arduous difficulties denying themselves, you know, the satisfactions of the flesh and, and that means everything from eating to drinking to everything else in between, you know, there were many "rules" that emerged about monasticism, not just the Rule of Saint Benedict, but many different kinds of forms of monasticism that came to be birthed all across the former remnants of the Roman Empire, then eventually we get the rule of Saint Benedict that crops up in Italy
It is tempting to speculate that an attenuated anti-oxidant response with elevated ROS in COPD [21, 22, 28, 36] may lead to an increased oxidant burden, possibly contributing to the observed mitochondrial defects in bronchial epithelial cells from COPD patients [6, 32, 37]
