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This disturbance persists until a more pronounced decrease in glomerular filtration rate occurs, along with a disruption in the elimination of these compounds [58]

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Similar content being viewed by others Introduction Drug-induced liver injury have now gradually become the leading causes of acute liver failure in developed countries and acetaminophen (APAP) abuse is the predominant cause of drug-induced hepatotoxicity with associated acute liver failure (Fisher and Curry 2019

However, statins commonly used have side reactions, especially muscle-related symptoms (SAMS), such as muscle weakness, pain, cramps, and severe condition of rhabdomyolysis