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Thus, in light of the poor clinical outcomes observed in the largest of the infliximab trials and the etanercept study, the use of these parenteral TNF inhibitors should be confined to clinical trials, and recommendations regarding specific therapy will need to await the results of these trials

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Fungi produce enzymes that can transform and stabilize soil inputs and fungi hyphae contribute to C sequestration and aggregation which are essential components of the soil's biological and physical health [288]