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[100], which monitored serum myocardial levels to assess cardiac injury markers in a treatment group receiving DOX, upon treatment with SFN, DOX-induced myocardial injury and inflammation was significantly reduced [99,100,101,102,103]

The complex I and complex III of ETC are able to produce the superoxide anion radical (O 2 ) and release it to both the matrix and the intermembrane space

Phosphorylation sites with missing values in more than 50% of samples were filtered out and the following key parameters were used: weight = 0, statistic = area.under.RES, output.score.type = NES, nperm = 1000 and min.overlap = 5